Unit INNOVATIVE THERAPIES IN PHARMACOLOGY
- Course
- Industrial pharmacy
- Study-unit Code
- A003607
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Marco Gargaro
- Teachers
-
- Marco Gargaro
- Hours
- 32 ore - Marco Gargaro
- CFU
- 4
- Course Regulation
- Coorte 2024
- Offered
- 2024/25
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- BIO/14
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- This course will provide students with a general overview of innovative immunology-based therapies currently under development for the treatment of rare diseases, oncological conditions, inflammatory disorders, and autoimmune diseases. In particular, the basic concepts of immunology necessary for understanding advanced next-generation cellular therapies will be provided.
- Reference texts
- Immunobiologia di Janeway, a cura di Kenneth Murphy, Casey Weaver, Massimo Locati, Piccin-Nuova Libraria, 2019.
- Educational objectives
- The main objective of this course is to provide students with the basic concepts for identifying and validating new immunological targets for the development of advanced and personalized pharmacological strategies.
- Prerequisites
- Successful completion of exams in General Pharmacology, Pharmacotherapy, and Experimental Pharmacology is required. Knowledge of these subjects is essential for students who wish to successfully pursue the course.
- Teaching methods
- Classroom lectures on all topics described in the syllabus delivered by the instructor. Student participation is encouraged to identify any learning difficulties.
- Other information
- Recommended frequency
- Learning verification modality
- The acquisition of all the described skills will be verified by means of an oral examination. Oral test consists of an interview of about 20 minutes aiming to ascertain the knowledge and understanding level acquired by the student on theoretical contents as indicated on the program.
Students with disabilities and/or DSA are invited to visit the page dedicated to the tools and measures envisaged and to agree in advance what is necessary with the teacher (https://www.unipg.it/disabilita-e -dsa). - Extended program
- This course will provide the basic concepts of immunology necessary for understanding advanced next-generation cellular therapies, including:
- Innate and adaptive immunity;
- Mechanisms of cellular communication;
- Differentiation of immune cells;
Furthermore, concepts for the development of cell-based biological drugs will be covered, such as:
- Engineered immune cells for the treatment of solid or hematological tumors (CAR-T, CAR-NK, CAR-Mac);
- Vaccines based on dendritic cells or viral vectors;
- Engineered stem cells with viral vectors for the treatment of rare diseases;
- Extracellular vesicles as carriers of biotherapeutics. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- Health and wellness