Unit MICROBIOLOGY
- Course
- Industrial pharmacy
- Study-unit Code
- A002513
- Curriculum
- In all curricula
- Teacher
- Donatella Pietrella
- Teachers
-
- Donatella Pietrella
- Hours
- 48 ore - Donatella Pietrella
- CFU
- 6
- Course Regulation
- Coorte 2024
- Offered
- 2025/26
- Learning activities
- Base
- Area
- Discipline mediche
- Academic discipline
- MED/07
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Cellular organization, metabolism and genetics of bacteria, fungi and viruses
The microbial virulence factors and infection transmission routes. Infection control strategies (vaccines and antimicrobials). Disinfection and Sterilization
Main microorganisms involved in human infections. - Reference texts
- Medical Microbiology
Patrick R Murray, Ken S. Rosenthal, Michael A. Pfaller.
Elsevier - Educational objectives
- The purpose of the present course is to acquire the following knowledge:
Cellular organization, metabolism, genetics of microorganisms
Positive and negative interactions between organism and man.
Pathogenetic mechanisms of microbial infections;
Vaccines in the containment of infection.
Molecular targets for antimicrobial drugs
Antibiotic resistance: mechanisms and prevention strategies - Prerequisites
- For the understanding of the course the student should have basic knowledge of cellular and molecular biology, anatomy, physiology and biochemistry.
- Teaching methods
- Lectures
- Other information
- Recommended attendance
- Learning verification modality
- The test consists of a discussion of the topics covered in class.
The knowledge of the subject, of the specific language acquired and the presentation ability will be evaluated.
For information on support services for students with disabilities and/or DSA, visit the page http://www.unipg.it/disabilita-e-dsa - Extended program
- History of Microbiology Prokaryotic and Eukaryotic microorganisms: general characteristics. Classification and Nomenclature of Microorganisms. The human microbiota Biotechnologies in the pharmaceutical field General Bacteriology Structures of the bacterial cell Classification and morphology of bacteria, bacterial metabolism, spores Bacterial physiology and metabolism: nutrition, respiration, fermentation Bacterial growth: bacterial count, growth curve, culture media Bacterial genetics (transduction, conjugation, and transformation) and gene regulation mechanisms Virulence Factors: Adhesins, capsule, exoenzymes, bacterial toxins (features and mechanism of action), biofilm formation Main classes (inhibitors of cell wall and protein synthesis, transcription, DNA replication, bacterial metabolism inhibitors) and related mechanisms of bacterial resistance Antibiogram. Clinically Relevant Bacteria** Clostridia, Staphylococci, Streptococci, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis, etc. General Virology. Viruses: classification, structure, and replication Viral pathogenesis Antiviral drugs Basic principles of laboratory diagnosis: serological and molecular diagnosis Main pathogenic viruses in humans: orthomyxoviruses, hepatitis viruses, HIV, HPV, arboviruses, coronaviruses, etc. Fungi: general overview Pathogenicity mechanisms Superficial and deep mycoses Antifungal drugs Protozoa: General characteristics Plasmodium and Toxoplasma. Modes of Transmission of Infectious Diseases. Infection Control Strategies Disinfection, sterilization Vaccines and immune sera.