Unit BIOTECHNOLOGICAL APPROACHES TO ONCOLOGICAL DISEASES

Course
Medical, veterinary and forensic biotechnological sciences
Study-unit Code
A001772
Curriculum
Medico
Teacher
Mario Mandala'
Teachers
  • Mario Mandala'
Hours
  • 42 ore - Mario Mandala'
CFU
6
Course Regulation
Coorte 2025
Offered
2026/27
Learning activities
Caratterizzante
Area
Discipline medico-chirurgiche e della riproduzione umana
Sector
MED/46
Type of study-unit
Opzionale (Optional)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
English
Contents
The biological background of anticancer agents: from chemo to personalised therapy and immunotherapy
Non melanoma skin cancers (NMSK): 1) Genomic features, Tumour microenvironment and clinical implications. 2) Discussion on clinical cases
Melanoma: Genomic features, Tumour microenvironment and clinical implications. 2) Discussion on clinical cases
Non small cell lung cancer (NSCLC) : Non Oncogene addicted tumors and treatment strategies. Discussion on clinical cases
NSCLC: Oncogene addicted tumors and treatment strategies. 
Discussion on clinical cases
Study of DNA and RNA with high-throughput technologies (NGS, Nanostring, Microarray)
Hereditary cancers: genomic analyses and impact on counseling and patient management
Intratumoral Microbioma: From the bench to bedside
Pharmacological 
features of new drugs
Reference texts
Frontal lessons with interactive Q&A sessions
Review articles from main scientific journals
Educational objectives
At the end of the course, students will be familiar with theoretical and
practical elements that guide the clinical application of biotecnological techniques, which are instrumental for diagnosis and therapy of the main
tumors.
Students will have the main elements that link the most modern biotechnological skills with the clinic, from the bench to the bedside
Finally, students will navigate in clinical cancer management by applying
the main knowledge for an integrated cancer approach
The internship in the lab will provide practical experience on most advanced high-throughput technologies (NGS, Nanostring, Microarray)
Prerequisites
Cell Biology
Basic pharmacology
Knowledge of the main laboratory techniques
Teaching methods
Frontal interactive lessons
Internship
Other information
Lessons will be enriched through the active interactions of students with basic, translational and clinical researchers
Learning verification modality
Esame scritto con domande a risposte multiple
Extended program
The biological background of anticancer agents: from chemo to personalised therapy
Non melanoma skin cancers (NMSK): 1) Genomic features, Tumour microenvironment and clinical implications. 2) Discussion on clinical cases
Melanoma: Genomic features, Tumour microenvironment and clinical implications. 2) Discussion on clinical cases
Non small cell lung cancer (NSCLC) : Non Oncogene addicted tumors and treatment strategies. Discussion on clinical cases
NSCLC: Oncogene addicted tumors and treatment strategies. 
Discussion on clinical cases
Study of DNA and RNA with high-throughput technologies (NGS, Nanostring, Microarray)
Hereditary cancers: genomic analyses and impact on counseling and patient management
Intratumoral Microbioma: From the bench to bedside
Pharmacological features of new drugs
Obiettivi Agenda 2030 per lo sviluppo sostenibile
health and well-being