Unit DRUG ANALYSIS
- Course
- Pharmaceutical chemistry and technology
- Study-unit Code
- 65010306
- Curriculum
- In all curricula
- Teacher
- Serena Massari
- Teachers
-
- Serena Massari
- Hours
- 69 ore - Serena Massari
- CFU
- 6
- Course Regulation
- Coorte 2025
- Offered
- 2026/27
- Learning activities
- Caratterizzante
- Area
- Discipline farmaceutico-alimentari
- Sector
- CHIM/08
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Understanding of the chemical, pharmaco-toxicological and analytical reactions of inorganic compounds described in the Official Pharmacopoeia. Pratical exercises on the main reactions for the qualitative detection of each chemical species studied.
- Reference texts
- 1.PDF files of lessons (UNISTUDIUM) https://www.unistudium.unipg.it/unistudium/login/index.php
2.Tuccari Parigi. Chimica analitica qualitativa (Ed. Atlas)
3.Barbetti-Quaglia. L'analisi qualitativa in chimica farmaceutica e tossicologia inorganica (Ed. Margiacchi Galeno )
4. Araneo. Chimica analitica qualitativa (Casa Editrice Ambrosiana, Milano)
5. Crea. Principi di chimica analitica (Ed. Zanichelli) - Educational objectives
- This course aims to provide students with the theoretical and practical knowledge of the chemical, pharmacotoxicological, and analytical aspects of the primary inorganic compounds listed in the Official Pharmacopoeia. Particular attention will be given to the reactions used for qualitative identification.
Upon completion of the course, students will have acquired the following:
- Theoretical and practical knowledge of proper conduct and best practices in a chemical-analytical laboratory.
- Theoretical knowledge of the qualitative analysis of inorganic compounds, particularly the substances listed in the Official Pharmacopoeia.
- practical knowledge of the main chemical reactions used to identify the studied compounds;
- knowledge of the structure, organization, and consultation of the Official Pharmacopoeia.
Upon completion of the course, students will be able to:
- Correctly and safely use the equipment, instruments, and glassware of a chemical analytical laboratory.
- apply a logical and experimental approach to analyzing and interpreting the chemical behavior of substances.
- identify an unknown inorganic compound by applying the most appropriate analytical method.
- Draft a technical-scientific report on laboratory activities.
- correctly consult and interpret monographs and information in the Official Pharmacopoeia.
Since this is the first chemistry laboratory course in the program, it provides the fundamental operational and methodological skills necessary for successfully completing the subsequent laboratory courses required for the degree. - Prerequisites
- Students must have a solid foundation in general and inorganic chemistry to successfully participate in the course. This foundation is essential for understanding the theoretical content and completing the practical laboratory activities included in the course.
Therefore, passing the General and Inorganic Chemistry exam is a prerequisite for enrollment. - Teaching methods
- The course consists of theoretical lectures and practical laboratory exercises.
The lectures cover all topics included in the syllabus and make use of electronic teaching materials (slides), which are made available to students prior to the lectures.
Laboratory activities take place at the Medicinal Analysis Laboratory and consist of 11 guided, individual-station exercises, each lasting four hours. During these activities, students perform the main analytical-qualitative reactions related to the chemical species under study. The practical sessions are closely integrated with the theoretical lectures, which explain the chemical principles and experimental procedures underlying the identification tests. Each practical activity is preceded by an introductory presentation aimed at reviewing the objectives, methodology, and operational procedures of the session. Throughout the practical sessions, constant interaction between the instructor and students is ensured through opportunities for discussion, clarification, and in-depth exploration of the theoretical and practical content. - Other information
- Attendance is compulsory: for theoretical lessons, at least 70% of presences; for the laboratory, no more than two absences.
- Learning verification modality
- Throughout the course, there will be ongoing practical assessments involving the qualitative identification of unknown compounds. These assessments are designed to monitor the progressive acquisition of the required practical skills.
The final exam consists of a practical laboratory assessment and an oral exam. The practical assessment involves identifying unknown compounds by applying the qualitative analytical methods learned during the course. The oral exam will be a discussion of the topics listed in the course syllabus.
This assessment evaluates the knowledge of and understanding of the theoretical and practical aspects related to the qualitative analysis of inorganic substances in pure form and in complex mixtures. It also evaluates the ability to identify inorganic active ingredients in medicinal products. Knowledge of, and ability to consult, the current Official Pharmacopoeia; mastery of scientific terminology; and clarity of presentation will also be evaluated.
The total exam duration varies depending on its progression, with the oral exam lasting an average of 30 minutes.
For more information about support services for students with disabilities and/or learning disabilities, please visit http://www.unipg.it/disabilita-e-dsa. - Extended program
- Theoretical Section
- Safety regulations and first-aid principles in the chemistry laboratory.
- Overview of glassware, instruments, and major laboratory equipment.
- Fundamental procedures and techniques of qualitative chemical analysis.
- Chemical, pharmacotoxicological, and analytical aspects of the main inorganic compounds described in the Italian and European Official Pharmacopoeias.
- Study of qualitative identification reactions for the main anions: carbonates and bicarbonates, sulfates, sulfites and metabisulfites, thiosulfates, phosphates, nitrates, halides, iodides, and borates.
- Study of qualitative identification reactions for the main cations: alkali and alkaline earth metals, ammonium, aluminum, silver, zinc, bismuth, and titanium.
- Application of qualitative analytical methods to pure substances, mixtures, and pharmaceutical preparations.
Practical Component
- Performing the main qualitative analytical reactions related to the chemical species studied.
- Sorting, separating, and identifying cationic and anionic mixtures of pharmaceutical interest.
- Application of thin-layer chromatography (TLC) for analytical purposes.
- Identification of inorganic ions present in pharmaceutical formulations and preparations.
- Interpretation of experimental results and correlation between laboratory observations and theoretical principles of qualitative analysis. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- Salute e benessere Istruzione di qualità