Unit MORPHOLOGY AND PATHOPHYSIOLOGY IN HUMANS

HUMAN ANATOMY

Code	GP003868
Location	PERUGIA
CFU	2
Teacher	Andrea Bartoli
Teachers	(Codocenza)
Hours	20 ore (Codocenza) -
Learning activities	Base
Area	Scienze biomediche
Sector	BIOS-12/A
Type of study-unit	Obbligatorio (Required)

NUTRITIONAL PHYSIOLOGY

Code	GP003869
Location	PERUGIA
CFU	2
Teacher	Alessandro Tozzi
Teachers	Alessandro Tozzi
Hours	20 ore - Alessandro Tozzi
Learning activities	Base
Area	Scienze biomediche
Sector	BIOS-06/A
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Elements of Neurophysiology Homeostasis and homeostatic mechanisms. Cellular transport and membrane potentials. Transmission and propagation of neural information. Somatic sensory nervous system and autonomic adrenergic nervous system. Elements of Skeletal Muscle Physiology Excitation-contraction coupling and force development and regulation. Spinal reflexes. Elements of Cardiovascular Physiology General organization of the cardiovascular system. Electrical and mechanical activity of the heart. Regulation of cardiac output and arterial pressure. Elements of Respiratory Physiology Respiratory mechanics, ventilation, diffusion, and transport of O2 and CO2. Elements of Gastrointestinal Physiology Functions of the digestive system. Role of the enteric nervous system, autonomic nervous system, and enteric endocrine system. Smooth muscle and motor functions of the gastrointestinal tract. Functions of the stomach, exocrine pancreas, and the liver’s role in digestion. Nutrient absorption. Urinary System: Overview of Nephron Physiology
Reference texts	Elementi di Fisiologia a cura di Roberto Poltronieri - EdiSES or Fisiologia umana - Elementi autori vari Edi-ermes
Educational objectives	Students will acquire knowledge of general physiology applied to workplace risk prevention, with a focus on homeostasis, neurophysiology, muscle, cardiovascular, respiratory, and metabolic physiology. This will enable them to assess the impact of working conditions on health and develop prevention strategies based on scientific evidence.
Prerequisites	Basics of cell biology, biochemistry, and anatomy.
Teaching methods	Lectures; projection of teaching materials in the classroom; ongoing assessments; publication of teaching materials on the university platform Unistudium.
Other information
Learning verification modality	Midterm Tests; Written Exam with Multiple-Choice and Open-Ended Questions. Use of the LibreEOL Platform.
Extended program	Elements of Neurophysiology • Homeostasis and homeostatic mechanisms. • Passive and active transport mechanisms. • Structure and functions of the nervous system. • Resting membrane potential. Graded potential and action potential. • Membrane receptors. Synaptic transmission. Propagation of nerve signals. • Properties of sensory receptors. Amplitude coding, frequency coding, and labeled line coding. • Somatic sensory nervous system. Tactile and thermal sensitivity. • Nociception and modulation mechanisms. • Autonomic adrenergic nervous system. Elements of Muscle Physiology • Skeletal muscle. • Neuromuscular synapse, excitation-contraction coupling, and cross-bridge cycle. • Muscle twitch and tetanic contraction. • Motor units. Mechanisms of force regulation. • Spinal reflexes. Flexor reflex; muscle spindle, stretch reflex. Elements of Cardiovascular Physiology • General organization of the cardiovascular system. • The heart. Cardiac electrical activity. • Cardiac mechanics: excitation-contraction coupling. Cardiac cycle. • Cardiac output and venous return. Regulation of cardiac output. • Blood pressure and regulatory mechanisms. Elements of Respiratory Physiology • Respiratory mechanics: airways and pulmonary ventilation. Thoracic-pulmonary balance. Inspiration and expiration. • Diffusion and transport of O2 and CO2. Elements of Gastrointestinal Physiology • Functions of the digestive system. • Role of the enteric nervous system, autonomic nervous system, and major hormones in digestive system regulation. • Smooth muscle. • Movements of the gastrointestinal tract. • Functions of the stomach. • Exocrine pancreatic secretions and regulation. • Role of the liver in fat digestion. • Digestion and absorption of nutrients.
Obiettivi Agenda 2030 per lo sviluppo sostenibile

GENERAL PATHOLOGY

Code	GP003870
Location	PERUGIA
CFU	2
Teacher	Andrea Bartoli
Teachers	Andrea Bartoli
Hours	20 ore - Andrea Bartoli
Learning activities	Base
Area	Scienze biomediche
Sector	MEDS-02/A
Type of study-unit	Obbligatorio (Required)