Unit PROPAEDEUTICS

ANESTHESIOLOGY

Code	50A00182
CFU	1
Teacher	Laura Marchesini
Teachers	Laura Marchesini
Hours	12 ore - Laura Marchesini
Learning activities	Caratterizzante
Area	Scienze interdisciplinari cliniche
Sector	MEDS-23/A
Type of study-unit	Obbligatorio (Required)

PHARMACOLOGY

Code	50A00187
CFU	2
Teacher	Ciriana Orabona
Teachers	Claudia Volpi (Codocenza) Ciriana Orabona
Hours	8 ore (Codocenza) - Claudia Volpi 16 ore - Ciriana Orabona
Learning activities	Caratterizzante
Area	Scienze medico-chirurgiche
Sector	BIOS-11/A
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	General Pharmacology Module General principles of pharmacology. Pharmacokinetics: drug absorption, distribution, metabolism, and elimination. Pharmacodynamics: mechanisms of drug action, pharmacological receptors, dose-response relationship, efficacy, and toxicity. Routes of administration and factors affecting drug response. Adverse drug reactions, drug interactions, and principles of pharmacovigilance. Pharmacotherapy Module General principles of pharmacotherapy. Drugs used in major cardiovascular, respiratory, inflammatory, and pain-related diseases. Drugs acting on the central and peripheral nervous systems. Antimicrobial agents: antibiotics and principles of anti-infective therapy. Contrast agents used in diagnostic imaging: classification, mechanisms of action, indications, contraindications, adverse reactions, and risk management. Drugs used in radiology and radiotherapy, including supportive drugs and radiopharmaceuticals. Principles of safety, appropriateness, and patient management in radiological settings.
Reference texts	Farmacologia generale e molecolare. Fondamenti. Fumagalli, Clementi. EDRA. Trattato di Farmacologia e Terapia. Annunziato, Di Renzo. Idelson Gnocchi.
Educational objectives	The course aims to provide students with the fundamental knowledge of general pharmacology and pharmacotherapy required to understand the clinical use of drugs and their application in diagnostic imaging and radiological therapy. At the end of the course, students will be able to: understand the principles of pharmacokinetics and pharmacodynamics; know the main mechanisms of drug action and their clinical applications; describe the major classes of drugs used in clinical practice; understand indications, contraindications, adverse effects, and drug interactions relevant to professional practice; understand the use of contrast agents and drugs employed in diagnostic imaging and radiotherapy; recognize and contribute to the management of the main adverse reactions to drugs and contrast media; acquire knowledge of the principles of safety, therapeutic appropriateness, and pharmacovigilance; integrate pharmacological knowledge with the professional practice of medical radiology technicians.
Prerequisites	Basic knowledge of anatomy, physiology, biology, and general pathology is required.
Teaching methods	The course consists of lectures supported by multimedia teaching materials (slides, diagrams, and supplementary materials). During the lectures, practical examples related to the clinical use of drugs, contrast agents, and radiopharmaceuticals in diagnostic and therapeutic settings will be discussed. Teaching activities will promote the integration of pharmacological knowledge with the professional and operational aspects of medical radiology practice, with particular attention to patient safety, management of adverse reactions, and appropriate use of drugs.
Other information	Teaching materials used during the course will be made available to students through institutional online platforms.
Learning verification modality	Learning assessment will be carried out through an oral examination aimed at evaluating the knowledge of the fundamental principles of general pharmacology and pharmacotherapy, the understanding of the clinical use of drugs and contrast agents, and the ability to use appropriate scientific terminology. Assessment will take into account the knowledge of drug mechanisms of action, therapeutic indications, adverse effects, and safety aspects relevant to the professional practice of medical radiology technicians.
Extended program	General Pharmacology Module Introduction to pharmacology. Definition of drugs and classification of medicinal products. Principles of pharmacokinetics: drug absorption, distribution, metabolism, and elimination. Bioavailability and half-life. Routes of drug administration. Pharmacodynamics. Pharmacological receptors and mechanisms of drug action. Dose-response relationship. Agonists and antagonists. Therapeutic index, efficacy, and toxicity. Drug safety. Adverse drug reactions, drug interactions, and principles of pharmacovigilance. Appropriate drug use and patient safety. Pharmacotherapy Module General principles of pharmacotherapy. Selection of pharmacological treatment, benefit/risk ratio, therapeutic appropriateness, and treatment adherence. Cardiovascular drugs. Main antihypertensive, antianginal, antiarrhythmic, and anticoagulant drugs. Therapeutic indications and adverse effects. Respiratory drugs. Bronchodilators, corticosteroids, and drugs used in major respiratory diseases. Anti-inflammatory and analgesic drugs. Nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, opioid and non-opioid analgesics. Clinical indications and adverse effects. Drugs acting on the nervous system. Anxiolytics, sedatives, antidepressants, antipsychotics, and anesthetics. Main pharmacological effects and adverse reactions. Anti-infective chemotherapy. General principles of antimicrobial therapy. Main classes of antibiotics and issues related to antibiotic resistance. Contrast agents. Classification of contrast agents used in diagnostic imaging. Iodinated and paramagnetic contrast media. Indications, contraindications, toxicity, and management of adverse reactions. Drugs and radiopharmaceuticals in radiology and radiotherapy. General principles of radiopharmaceuticals. Drugs used in the preparation and management of patients undergoing diagnostic and therapeutic procedures. Supportive drugs used in radiotherapy. Safety and patient management. Prevention and management of adverse reactions to drugs and contrast agents. Principles of safety, patient monitoring, and interdisciplinary collaboration in radiological settings.
Obiettivi Agenda 2030 per lo sviluppo sostenibile	Goal 3: Health and well-being

ONCOLOGY

Code	A000442
CFU	1
Teacher	Mario Mandala'
Teachers	Mario Mandala'
Hours	12 ore - Mario Mandala'
Learning activities	Caratterizzante
Area	Scienze interdisciplinari cliniche
Sector	MEDS-09/A
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Tumors definition Tumors classification Tumors grading Tumors staging Diagnosis of tumors (lab and imaging tests, tumor markers) Tumors epidemiology (incidence, prevalence and mortality) Primary prevention of tumors Secondary prevention of tumors (early diagnosis) Oncological patients management (multisciplinary oncological groups, regional oncological network) Principles of medical therapy in oncology Toxicity of oncological treatments Supportive and palliative therapy in oncology Oncological emergencies Update on the prophylaxis and therapy of some symptoms and adverse events of antineoplastic agents. Diagnostic and therapeutic approach to some tumors: breast, lung, prostate and colo-rectal cancers Myths and misconceptions on cancer
Reference texts	Slides shared with students AIOM Guidelines
Educational objectives	Basic knowledge of general pathology aspects, of tumors diagnostics and therapies.
Prerequisites	Notions on the tumors characteristics, on the modality of prevention and early diagnosis, on the diagnostic tests and on therapies (from surgery to radiotherapy, from hormonotherapy to target therapies and to immunotherapy) including supportive therapies and palliative care with the objective to have a wide panorama of the medical oncology.
Teaching methods	Frontal interactive lessons
Other information	Interactive clinical cases
Learning verification modality	Multiple choices questions
Extended program	Cancer definition (difference between normal and neoplastic cells, cancer metastases, tumors classification, grades and stages of tumors); epidemiology and risk factors; primary prevention in the general population and in patients at risk; secondary prevention: screening tests; tumor diagnosis and TMN stadiation; principles of locoregional therapy (surgery and radiotherapy); general concepts of systemic anti-tumor therapy with reference to chemotherapy, hormone therapy, molecular target therapy, immunotherapy. Main organ toxicities of systemic therapies and their management with particular reference to bone marrow toxicity, gastrointestinal toxicity, skin toxicity; cardiotoxicity, pulmonary and neurological toxicity, autoimmune toxicity during immunotherapy. Oncological emergencies (superior vena cava syndrome, spinal cord compression, brain metastases, hypercalcemia, hyponatremia), infectious emergencies and septic shock, metabolic syndromes. Treatment of neoplastic pain in oncological patients.
Obiettivi Agenda 2030 per lo sviluppo sostenibile	Promoting health, reducing inequalities

PATIENT HANDLING AND MOVEMENT

Code	A000443
CFU	1
Learning activities	Caratterizzante
Area	Scienze della prevenzione e dei servizi sanitari
Sector	MEDS-26/C
Type of study-unit	Obbligatorio (Required)

PSYCHOLOGY

Code	A000444
CFU	1
Teacher	Claudia Mazzeschi
Teachers	Claudia Mazzeschi
Hours	12 ore - Claudia Mazzeschi
Learning activities	Affine/integrativa
Area	Attività formative affini o integrative
Sector	PSIC-04/A
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	The course aims to introduce the student to the knowledge of the biopsychosocial model for defining health, the medical approach and the psychological approach, the functioning of personality and defence mechanisms, emotions, and the human reaction in relation to diagnosis.
Reference texts	- Munno, D. (2008). Psicologia clinica per medici. Chapters: 1, 3, 4 - Articles covered in the lecture Further reading: - Lingiardi, V. (2018). Diagnosi e destino. Giulio Einaudi Editore. - Pervin, A.l., John, O. (1997). La scienza della personalità. Raffaello Cortina Editore. Chap. 1, 3
Educational objectives	The main objective of the course is to provide students with knowledge and skills concerning human mechanisms and reactions when faced with a disease diagnosis.
Prerequisites	To understand the planning and evaluation of psychological interventions, it is advisable to have a basic knowledge of the biomedical model of health. Furthermore, it is advisable to be able to read and comprehend scientific articles in English.
Teaching methods	The lectures will take place as face-to-face lecture for most of the arguments. Student’s active interaction is welcome.
Other information	The student can check the course material and any announcements/notices from the Professor on UniStudium during the course.
Learning verification modality	Written and/or oral examination. For written examination: 15 MULTIPLE-CHOICE QUESTIONS ON THE SYLLABUS. EVALUATION: 2 = CORRECT ANSWER; 0 = WRONG ANSWER OR NOT GIVEN If the student intends to take the examination a year before the year scheduled in the study plan, it is recommended that he/she attend the cycle of lectures and take the examination in the first useful call after the lectures have ended, thus respecting the semester in which the course is scheduled.
Obiettivi Agenda 2030 per lo sviluppo sostenibile	Goal 3. Ensure healthy lives and promote well-being for all at all ages