Unit APPLIED BIOLOGY
- Course
- Pharmaceutical biotechnologies
- Study-unit Code
- GP003563
- Curriculum
- In all curricula
- Teacher
- Rita Romani
- Teachers
-
- Rita Romani
- Hours
- 52 ore - Rita Romani
- CFU
- 6
- Course Regulation
- Coorte 2026
- Offered
- 2026/27
- Learning activities
- Caratterizzante
- Area
- Discipline biotecnologiche comuni
- Sector
- BIOS-10/A
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Course objectives are: to deepen the knowledge of the structure and cellular functions, genesis of eso vesicles and their role in cell communication and the possible diagnostic and therapeutic applications, depending on the biological niches and finally explore some mechanism of transmission of hereditary characteristics
- Reference texts
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter "Biologia molecolare della cellula" ZanichelliSome topics covered during the course, for their relevance will have to be supplemented with scientific articles because not yet available in textbooks.
- Educational objectives
- The objectives of the course are: to deepen knowledge on alternative cellular communication systems that can be used in biotechnological protocols
- Prerequisites
- To achieve the training objectives, the student requires knowledge of Cell Biology and Molecular Biology.
- Teaching methods
- Practical and theoretical classes
- Other information
- For information on support services for students with disabilities and/or DSA visit the page
http://www.unipg.it/disabilita-e-dsa - Learning verification modality
- Oral exam consisting of an about 20-minute discussion aimed at ascertaining the degree of comprehension of the student about theoretical and methodological contents of the program.
- Extended program
- Post synthetic fate of proteins. Vesicular trafficking and vesicle role in cellular communication. Biotechnological applications of eso vesicles. Symmetric and asymmetric cell division. Cellular aging process: cellular senescence, autophagy, repair systems of DNA damage.Stem cells and biological niches.Exceptions to Mendel's laws, genetic imprinting, uniparental disomy genetic mosaicism, chimeras, multifactorial traits. Mitochondrial inheritance. Main techniques applied in medical genetics for the diagnosis
Practical exercises:
Stem cell differentiation: medium preparation , histochemical stains and PCR in order to demostrate the differentiation. Formation of embryoid bodies. Isolation extracellular vesicles, RNA extraction, PCR - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- health and wellness