Unit BIOMEDICAL TECHNOLOGY

Course
Pharmaceutical biotechnologies
Study-unit Code
GP003552
Curriculum
In all curricula
Teacher
Ilaria Bellezza
Teachers
  • Ilaria Bellezza
  • Davide Chiasserini (Codocenza)
Hours
  • 40 ore - Ilaria Bellezza
  • 12 ore (Codocenza) - Davide Chiasserini
CFU
6
Course Regulation
Coorte 2026
Offered
2026/27
Learning activities
Caratterizzante
Area
Discipline biotecnologiche comuni
Sector
BIOS-07/A
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
1CFU english
Contents
Aminoacids, Primary, secondary, tertiary, quaternary structures, modifications that control protein activity. Advanced proteomic techniques. Bioinformatics for proteomics.
Reference texts
Nelson, Cox Principi di Biochimica di Lehninger, Zanichelli
Educational objectives
The main goal of the course is to provide students with the basics to understand the properties of proteins as possible pharmacological targets.

The main skills acquired will be:

-Knowledge of the spatial organization of proteins and the interactions that stabilize it

- Understanding the structure and function of proteins

-Major changes that govern the activity of proteins.
Knowledge of the main proteomic techniques and data analysis of high-throughput omics data.
Prerequisites
The understanding of most of the topics requires the knowledge of general biochemistry. Knowledge of these issues is a prerequisite for the student who wants to follow the course with profit.
Teaching methods
lectures and laboratory activities
Other information

Learning verification modality
Oral exams of theoretical nature, consisting of questions covering the topics addressed. The exam is finalized to demonstrate the knowledge and the understanding of the student.
Extended program
Aminoacids, Primary, secondary, tertiary, quaternary structures, modifications that control protein activity.
Omics technologies for protein analysis: sample preparation, mass spectrometry, analysis of post-translational modifications, proximity extension assays, and aptamer-based technologies. Bioinformatic analysis of differential protein expression and functional proteome analysis techniques.
Obiettivi Agenda 2030 per lo sviluppo sostenibile